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Monoclonal Anti-DC-SIGN [8B6] antibody produced in mouse

品牌
Sigma-Aldrich
货号
SAB3501155
规格纯度
affinity purified immunoglobulin (IgG)
参考价格
4802.96 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Monoclonal Anti-DC-SIGN [8B6] antibody produced in mouse
产品介绍:

产品说明

一般描述

DC-SIGN Monoclonal Antibody: Dendritic cells (DCs) that control immune responses were recently found to capture and transport HIV from the mucosal area to remote lymph nodes, where DCs hand over HIV to CD4+ T lymphocytes. DCs also amplify the amount of virus and extend the duration of viral infectivity. Multiple strains of HIV-1, HIV-2 and SIV bind to DCs via DC-SIGN. ICAM-3 is the natural ligand for DC-SIGN. A DC-SIGN homologue (termed DC-SIGNR, L-SIGN, and DC-SIGN2) was identified recently. DC-SIGN forms a novel gene family with DC-SIGNR and many alternatively spliced isoforms of DC-SIGN and DC-SIGNR are known to exisit. The expression of DC-SIGN was found in mucosal tissues including placenta, small intestine, and rectum.

免疫原

A recombinant His-tagged protein fragment corresponding to the extracellular region of human DC-SIGN.

应用

DC-SIGN antibody can be used for detection of DC-SIGN in Western Blot at 1 - 2 mg/mL and in immunohistochemistry at 5 - 10 mg/mL. Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

外形

Supplied in PBS containing 0.02% sodium azide.

产品性质

质量水平100
生物来源mouse
偶联物unconjugated
抗体形式affinity purified immunoglobulin (IgG)
antibody product typeprimary antibodies
克隆monoclonal
形式liquid
species reactivityhuman
浓度1 mg/mL
technique(s)immunohistochemistry: suitable
western blot: suitable
同位素/亚型IgG1, kappa
UniProt登记号Q9NNX6
运输wet ice
储存温度−20℃
Gene Informationhuman ... CD209(30835)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKnwg
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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