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Monoclonal Anti-FGF8 antibody produced in mouse

品牌
Sigma-Aldrich
货号
SAB1403813
规格纯度
clone 2A11, purified immunoglobulin, buffered aqueous solution
参考价格
5001.78 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
-+
产品名称:
Monoclonal Anti-FGF8 antibody produced in mouse
MGC149376
HBGF-8
AIGF
产品介绍:

产品说明

一般描述

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The adult expression of this gene is restricted to testes and ovaries. Temporal and spatial pattern of this gene expression suggests its function as an embryonic epithelial factor. Studies of the mouse and chick homologs revealed roles in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination. The alternative splicing of this gene results in four transcript variants. (provided by RefSeq)

免疫原

FGF8 (NP_149354, 65 a.a. ~ 133 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
SRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSR VRVRGAETGLYICMNKKGK

生化/生理作用

Fibroblast growth factor-8 (FGF-8) stimulates the proliferation and activation of cells that express the FGF receptors. It has a role in embryogenesis. FGF8b, an isoform of FGF-8, is expressed in prostate cancer.

外形

Solution in phosphate buffered saline, pH 7.4

基本信息

NACRESNA.41

产品性质

质量水平100
生物来源mouse
偶联物unconjugated
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆2A11, monoclonal
形式buffered aqueous solution
分子量antigen ~33.6 kDa
species reactivityhuman
technique(s)capture ELISA: suitable
indirect ELISA: suitable
proximity ligation assay: suitable
同位素/亚型IgG2aκ
NCBI登记号NM_033164
UniProt登记号P55075
运输dry ice
储存温度−20℃
Gene Informationhuman ... FGF8(2253)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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