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Monoclonal Anti-HLA-DPB1 antibody produced in mouse

品牌
Sigma-Aldrich
货号
SAB1403919
规格纯度
clone 2D3, ascites fluid
参考价格
5045.46 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Monoclonal Anti-HLA-DPB1 antibody produced in mouse
DPB1
HLA-DP1B
产品介绍:

产品说明

一般描述

HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. (provided by RefSeq)

免疫原

HLA-DPB1 (AAH13184, 1 a.a. ~ 258 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
MMVLQVSAAPRTVALTALLMVLLTSVVQGRATPENYVYQGRQECYAFNGTQRFLERYIYNREEYARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRVCRHNYELDEAVTLQRRVQPKVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNGDWTFQILVMLEMTPQQGDVYICQVEHTSLDSPVTVEWKAQSDSAQSKTLTGAGGFVLGLIICGVGIFMHRRSKKVQRGSA

外形

Clear solution

产品性质

生物来源mouse
偶联物unconjugated
抗体形式ascites fluid
antibody product typeprimary antibodies
克隆2D3, monoclonal
分子量antigen ~54.49 kDa
species reactivityhuman
technique(s)indirect ELISA: suitable
western blot: 1:500-1:1000
同位素/亚型IgG
NCBI登记号BC013184
UniProt登记号P04440
运输dry ice
储存温度−20℃
Gene Informationhuman ... HLA-DPB1(3115)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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