产品说明
一般描述
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake. A variety of mutant alleles with changes in the coding region have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5′ region and with the IGF2 gene at the 3′ region. (provided by RefSeq)
免疫原
KLH-conjugated human Proinsulin peptide (NP_000198, 48 a.a. ~ 62 a.a)
Sequence
CFFYTPKTRREAEDLQ
外形
Solution in phosphate buffered saline, pH 7.4
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | mouse |
| 偶联物 | unconjugated |
| 抗体形式 | purified immunoglobulin |
| antibody product type | primary antibodies |
| 克隆 | 7C8, monoclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen ~1.65 kDa |
| species reactivity | human |
| technique(s) | indirect ELISA: suitable |
| 同位素/亚型 | IgG3κ |
| NCBI登记号 | NM_000207 |
| UniProt登记号 | P01308 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... INS(3630) |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
