产品说明
一般描述
Inositol 1,4,5-trisphosphate receptor, type 1 (ITPR1) is highly expressed in the rat brain and is also seen in the heart. It possesses an inositol-triphosphate binding domain, a channel-forming region and a regulatory region. ITPR1 is composed of 2749 amino acids. The gene ID for the protein is 25262.
特异性
Detects ~300 kDa. Does not recognize type 2 or type 3 IP3R′s.
免疫原
Fusion protein amino acids 2680-2749 (cytoplasmic carboxyl terminus) of rat type1 IP3R inositol 1,4,5-triphosphate receptor type 1, Itpr1
应用
Monoclonal Anti-ITPR1 antibody produced in mouse has been used for Western blotting.
生化/生理作用
Inositol 1,4,5-trisphosphate receptor, type 1 (ITPR1) takes part in Ca2+ signaling on binding to its ligand, inositol 1,4,5-trisphosphate.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Solution in PBS, pH 7.4, 50% glycerol, and 0.09% sodium azide
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
NACRES | NA.41 |
产品性质
生物来源 | mouse |
偶联物 | unconjugated |
抗体形式 | purified immunoglobulin |
antibody product type | primary antibodies |
克隆 | S24-18, monoclonal |
形式 | buffered aqueous glycerol solution |
分子量 | antigen predicted mol wt 300 kDa |
species reactivity | mouse, rat, human |
浓度 | 1 mg/mL |
technique(s) | immunohistochemistry: suitable immunoprecipitation (IP): suitable western blot: suitable |
同位素/亚型 | IgG1 |
NCBI登记号 | NP_001007236.1 |
UniProt登记号 | Q14643 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | rat ... Itpr1(25262) |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich