产品说明
一般描述
Nuclear receptor corepressor 1 (NCoR) is an important transcriptional regulator or a steroid receptor coregulatory protein. In normal prostate, NCOR1 is found in the cytoplasm and nuclei of secretory epithelial cells. NCoR gene is located on human chromosome 17p.
免疫原
Purified recombinant fragment of NCOR1 (aa1-192) expressed in E.coli.
Mouse monoclonal antibody raised against NCOR1
生化/生理作用
Nuclear receptor corepressor 1 (NCoR) acts as a corepressor of unliganded thyroid receptor (TR). NCOR1 controls bicalutamide-dependent and independent transcription. It blocks invasion and metastasis. NCOR1 also controls CHEK1 (checkpoint kinase 1).
外形
Ascitic fluid containing 0.03% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
NACRES | NA.41 |
产品性质
生物来源 | mouse |
偶联物 | unconjugated |
抗体形式 | ascites fluid |
antibody product type | primary antibodies |
克隆 | 7A7A9, monoclonal |
species reactivity | human |
technique(s) | direct ELISA: 1:10,000 immunohistochemistry: 1:200-1:1,000 western blot: 1:500-1:2,000 |
同位素/亚型 | IgG1 |
NCBI登记号 | NM_006311 |
UniProt登记号 | O75376 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... NCOR1(9611) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich