产品说明
一般描述
The NOTCH1 gene is mapped to human chromosome 9q34.3. In mice, Notch1 is highly expressed in immature neurons of hippocampus. Notch1 is localized to renal epithelial cells and podocytes of metanephros.
免疫原
Fusion protein amino acids 20-216 (extracellular N-terminus, EGF-like domains 1-5) of mouse Notch1
生化/生理作用
The Notch signaling pathway regulates endothelial-cell differentiation, proliferation and apoptosis, and is essential for the development, maintenance and remodeling of the vascular system. Notch signaling pathway is involved in the development and progress of cardiovascular diseases. Notch1 function is predominant in developing kidney compared to compared to the mature organ.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
PBS pH7.4, 50% glycerol, 0.09% sodium azide
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 质量水平 | 100 |
| 生物来源 | mouse |
| 偶联物 | Peridinin-Chlorophyll-Protein Complex |
| 抗体形式 | purified immunoglobulin |
| antibody product type | primary antibodies |
| 克隆 | S253-32, monoclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen predicted mol wt >270, ~120 kDa |
| species reactivity | rat, mouse, human |
| 浓度 | 1 mg/mL |
| technique(s) | immunocytochemistry: suitable western blot: suitable |
| 同位素/亚型 | IgG1 |
| NCBI登记号 | NP_032740.3 |
| UniProt登记号 | Q07008 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | mouse ... Notch1(18128) |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
