产品说明
免疫原
Full-length human RPA-14 expressed in E. coli..
应用
For IP: Use at a concentration of 0.1 - 2 μg/mL. For WB: Use at a concentration of 0.1 - 2 μg/mL. For IHC-P: 1:100-1:1000. Predicted molecular weight: 14 kDa. Optimal dilutions/concentrations should be determined by the researcher.
生化/生理作用
Replication protein A (RPA) is a single-stranded DNA binding protein. Human RPA is a heterotrimeric protein containing subunits of 70, 32 and 14 kDa. This protein complex is highly conserved in eukaryotes and is essential in DNA replication, homologous recombination and nucleotide excision repair. RPA has been shown to be a target for DNA-dependent protein kinase (DNA-PK) ataxia telangiectasia-mutated gene (ATM) and a cyclin dependent protein kinase.
特点和优势
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外形
Phosphate-buffered saline, no preservative added.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
产品性质
生物来源 | mouse |
偶联物 | unconjugated |
抗体形式 | purified immunoglobulin |
antibody product type | primary antibodies |
克隆 | 11.1 monoclonal |
形式 | liquid |
分子量 | 14 kDa |
species reactivity | human, mouse |
浓度 | 1 mg/mL |
technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:1000 immunoprecipitation (IP): suitable western blot: 0.1-2 μg/mL |
同位素/亚型 | IgG1 |
UniProt登记号 | P35244 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... RPA3(6119) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich