产品说明
一般描述
N-methyl-2-pyridone-5-carboxamide (2PY) is one of the end products of nicotinamide-adenine dinucleotide (NAD) degradation. Increased serum 2PY concentrations are observed in chronic renal failure (CRF) patients, which along with the deterioration of kidney function and its toxic properties (significant inhibition of PARP-1), suggests that 2PY is an uremic toxin.
应用
Metabolomics research
基本信息
经验(实验)分子式 | C7H8N2O2 |
分子量 | 152.15 |
MDL编号 | MFCD00457283 |
产品性质
质量水平 | 100 |
测定 | ≥95% (HPLC) |
形式 | solid |
Sigma-Aldrich