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Nedaplatin

奈达铂(Nedaplatin)

品牌
Sigma-Aldrich
CAS
95734-82-0
货号
SML2514
包装型号
规格纯度
参考价格
1561.34 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
95734-82-0
Nedaplatin
Cis-Diammine (Glycolato)Platinum
奈达铂(Nedaplatin)
产品介绍:

产品说明

生化/生理作用

Nedaplatin is a second-generation cisplatin analog with antineoplastic activity. Containing a novel ring structure in which glycolate is bound to the platinum by a bidentate ligand, nedaplatin forms reactive platinum complexes that bind to nucelophillic groups in DNA, resulting in intrastrand and interstrand DNA cross-links, apoptosis and cell death. Nedplatin is less nephrotoxic and neurotoxic compared to both cisplatin and carboplatin.

基本信息

经验(实验)分子式C2H8N2O3Pt
分子量303.17

产品性质

形式powder
储存温度2-8℃
InChI1S/C2H4O3.2H2N.Pt/c3-1-2(4)5;;;/h3H,1H2,(H,4,5);2*1H2;/q;2*-1;+2
InChI keyKLNFSAOEKUDMFA-UHFFFAOYSA-N

安全信息

象形图GHS06GHS08
警示用语:Danger
危险声明H300 - H315 - H317 - H319 - H334 - H335 - H350
预防措施声明P201 - P261 - P280 - P301 + P310 + P330 - P304 + P340 + P312 - P308 + P313
危险分类Acute Tox. 2 Oral - Carc. 1B - Eye Irrit. 2 - Resp. Sens. 1B - Skin Irrit. 2 - Skin Sens. 1B - STOT SE 3
靶器官Respiratory system
储存分类代码6.1B - Non-combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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