产品说明
特点和优势
NHS-S-S-dPEG®4-biotin is used extensively to label molecules that contain a free amine with biotin. This dPEG® spacer imparts a high degree of water solubility to the biotin label. For biotinylated peptides and proteins, the dPEG® spacer dramatically reduces aggregation and precipitation of the modified molecule and reduces non-specific binding of the molecule, both of which are common problems with molecules that have been biotinylated with the widely used NHS-LC-biotin. NHS-S-S-dPEG®4-biotin contains a disulfide group in the linear chain, allowing the biotin to be cleaved reductively from the labeled molecule.
法律信息
Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign
基本信息
经验(实验)分子式 | C30H49N5O11S3 |
分子量 | 751.93 |
PubChem化学物质编号 | 329823886 |
NACRES | NA.22 |
产品性质
测定 | >90% |
形式 | solid or viscous liquid |
reaction suitability | reaction type: Biotinylations reagent type: cross-linking reagent |
官能团 | disulfide |
聚合物结构设计 | shape: linear functionality: monofunctional |
运输 | ambient |
储存温度 | −20℃ |
SMILES string | O=C(NCCSSCCC(ON1C(CCC1=O)=O)=O)CCOCCOCCOCCOCCNC(CCCCC2C3NC(NC3CS2)=O)=O |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich