Nimorazole

产品名称：

6506-37-2
Nimorazole
K1900
NSC 107524
NSC-107524
K 1900
4-(2-(5-Nitro-1H-imidazol-1-yl)ethyl)morpholine
NSC107524
K-1900

产品介绍：

产品说明

生化/生理作用

Nimorazole is a nitroimidazole-based hypoxic cell-radiation sensitizer with less toxicity than etanidazole or misonidazole. Under low oxygen (hypoxic) condition, reductive activation of its 5-nitroimidazole moiety leads to enhanced adduct formation with reduced glutathione, which form the basis of cancer/tumour-selective radiation sensitization. Nimorazole is also a known anti-infective agent against trichomoniasis, an infectious disease caused by the protozoan parasite Trichomonas vaginalis.

基本信息

经验(实验)分子式	C₉H₁₄N₄O₃
分子量	226.23
EC 号	229-394-4

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 30 mg/mL, clear
储存温度	2-8℃
InChI	1S/C9H14N4O3/c14-13(15)9-7-10-8-12(9)2-1-11-3-5-16-6-4-11/h7-8H,1-6H2
InChI key	MDJFHRLTPRPZLY-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Danger
危险声明	H340 - H361d
预防措施声明	P201 - P308 + P313
危险分类	Muta. 1B - Repr. 2
储存分类代码	6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable