产品说明
一般描述
This is the nuclear NMNAT isoform. It catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. It can also use the deamidated form of nicotinic acid mononucleotide (NAMN) as substrate with the same efficiency. It interacts with PARP-1/ARTD1. It protects against axonal degeneration following mechanical or toxic insults. It is widely expressed.
外形
1 mg/mL in 50 mM sodium phosphate, pH 8.0 containing 300 mM sodium chloride, 2 mM DTT and 10% glycerol.
基本信息
| NACRES | NA.32 |
产品性质
| 生物来源 | human |
| 重组 | expressed in E. coli |
| 测定 | ≥95% (SDS-PAGE) |
| 形式 | liquid |
| 分子量 | monomer ~333 kDa (Human full-length NMNAT1 aa 1-279 is fused at the N-terminus to a His-tag.) |
| 包装 | pkg of 10 and 50 μg |
| 浓度 | 1 mg/mL |
| UniProt登记号 | Q9HAN9 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... NMNAT1(64802) |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
