Nolatrexed dihydrochloride

产品名称：

152946-68-4
Nolatrexed dihydrochloride
AG 337
2-Amino-6-methyl-5-(4-pyridinylthio)-4(1H)-quinazolinone dihydrochloride

产品介绍：

产品说明

生化/生理作用

Nolatrexed dihydrochloride is a water-soluble lipophilic quinazoline folate analog that exhibits potent antineoplastic activity. Nolatrexed is a potent thymidylate synthase inhibitor that inhibits thymine synthesis followed by inhibition of DNA replication.

基本信息

经验(实验)分子式	C₁₄H₁₂N₄OS · 2HCl
分子量	357.26
MDL编号	MFCD26960887

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
储存条件	desiccated
颜色	white to beige
溶解性	H₂O: 2 mg/mL, clear
储存温度	2-8℃
SMILES string	NC1=NC(C2=C(N1)C=CC(C)=C2SC3=CC=NC=C3)=O

安全信息

象形图
警示用语：	Warning
危险声明	H341 - H361fd
预防措施声明	P201 - P202 - P280 - P308 + P313 - P405 - P501
危险分类	Muta. 2 - Repr. 2
储存分类代码	11 - Combustible Solids
WGK	WGK 3