NS6180

产品名称：

353262-04-1
NS6180
4-[[3-(Trifluoromethyl)phenyl]methyl]-2H-1,4-benzothiazin-3(4H)-one

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

NS6180 is a novel inhibitor of the intermediate-conductance Ca2+-activated K+ channel (K_Ca3.1) The IC₅₀ of NS6180 against cloned human K_Ca3.1 is 9 nM. The compound blocks proliferation and production of IL-2 and IFNγ with sub-micromolar potencies in either ConA or PMA/ionomycin challenged rat splenocytes.

基本信息

经验(实验)分子式	C₁₆H₁₂F₃NOS
分子量	323.33
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 20 mg/mL, clear
储存温度	2-8℃

安全信息

象形图
警示用语：	Warning
危险声明	H317 - H411
预防措施声明	P273 - P280 - P302 + P352
危险分类	Aquatic Chronic 2 - Skin Sens. 1
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable