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PADI-2 human

品牌
Sigma-Aldrich
货号
SRP0327
规格纯度
recombinant, expressed in baculovirus infected Sf9 cells, ≥60% (SDS-PAGE)
参考价格
8831.52 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
PADI-2 human
Peptidyl arginine deiminase, type II
人 PADI-2
产品介绍:

产品说明

一般描述

Human PADI2, also known as Peptidyl arginine deiminase, type II, (GenBank Accession No. NM_007365), amino acids 1-665 (end) with C-terminal FLAG-tag, MW= 77kDa, expressed in a Baculovirus infected Sf9 cell expression system. Peptidyl arginine deiminase, protein-2 (PADI2) is mapped to human chromosome 1p36. It is expressed in Sertoli cells at the time of testicular development.

应用

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. PADI-2 human has been used in in vitro binding assays.

生化/生理作用

Peptidyl arginine deiminase, protein-2 (PADI2) promotes protein citrullination and represses the multiplication of cells. It helps to transform the amino acid arginine in a protein into amino acid citrulline. PADI2 participates in epigenetic mechanisms. It is linked with rheumatoid arthritis.

外形

Formulated in 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 80 ng/uL Flag peptide, 3 mMDTT, and 20% Glycerol.

产品性质

生物来源human
重组expressed in baculovirus infected Sf9 cells
测定≥60% (SDS-PAGE)
形式aqueous solution
分子量 77 kDa
包装pkg of 10 μg
NCBI登记号NM_007365
UniProt登记号Q9Y2J8
运输dry ice
储存温度−70℃
Gene Informationhuman ... PADI2(11240)

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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