产品说明
一般描述
Progranulin, also called proepithelin and PC cell-derived growth factor, is a single precursor protein of granulins which are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. Granulins are a variety of active, 6.0 kDa peptides and named granulin A (epithelin 1), granulin B (epithelin 2), granulin C, etc. Both the peptides and intact progranulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis. Progranulin Human Recombinant fused to FLAG at C-terminus produced in HEK is a single, glycosylated, polypeptide chain containing 593 amino acids and having a molecular mass of 88.0 kDa. The Progranulin is purified by standard chromatographic techniques.
外形
Sterile filtered clear solution in PBS
产品性质
| 生物来源 | human |
| 重组 | expressed in HEK 293 cells |
| 测定 | ≥90% (HPLC) ≥90% (SDS-PAGE) |
| 形式 | liquid |
| 分子量 | 88.0 kDa |
| 包装 | pkg of 10 μg |
| 浓度 | 0.5 mg/mL |
| 杂质 | Endotoxin, tested |
| NCBI登记号 | P28799 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... GRN(2896) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
