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Progranulin rat

品牌
Sigma-Aldrich
CAS
139316-59-9
货号
SRP8017
规格纯度
recombinant, expressed in HEK 293 cells, FLAG® tagged, >95% (SDS-PAGE)
参考价格
2963.99 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
139316-59-9
Progranulin rat
PEPI
Proepithelin
产品介绍:

产品说明

一般描述

Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signaling cascades that control cell cycle progression and cell motility. Its function in the central nervous system is of interest, as mutations in the PGRN gene were found in cases of frontotemporal degeneration (FTLD). In addition, PGRN has also been linked to tumorigenesis. Progranulin is a biomarker for FTLD, other types of Alzheimer′s Disease (AD) and potentially for MCI (Mild Cognitive Impairment). Additionally, PGRN is described as a new ligand of TNF receptors and a potential therapeutic against inflammatory disease like arthritis.

外形

Lyophilized from 0.2 μm-filtered solution in PBS.

重悬

Reconstitute with 100 μL deionized water.

其他说明

Signal peptide and rat progranulin (aa 1-602) are fused at the C-terminus to a FLAG®-tag.

法律信息

FLAG is a registered trademark of sigma-aldrich Co. LLC

基本信息

NACRESNA.32

产品性质

生物来源rat
重组expressed in HEK 293 cells
标签FLAG® tagged
测定>95% (SDS-PAGE)
形式lyophilized
分子量 ~65 kDa by SDS-PAGE
包装pkg of 10 μg
manufacturer/tradenamesigma-aldrich
储存条件avoid repeated freeze/thaw cycles
杂质<0.1 EU/μg endotoxin, tested
颜色 white
UniProt登记号P23785
运输wet ice
储存温度−20℃
Gene Informationrat ... Grn(29143)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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