产品说明
一般描述
PYCR1 is a universal housekeeping enzyme that catalyzes the NAD (P) H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP (+) in some cell types. It forms a homopolymer and localizes to the mitochondrion. Defects in PYCR1 are the cause of cutis laxa autosomal recessive type 2B (ARCL2B). Recombinant human PYCR1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
外形
0.5 mg/mL in 20 mM Tris-HCl buffer (pH 8.5) containing 10% glycerol.
基本信息
| NACRES | NA.32 |
产品性质
| 生物来源 | human |
| 重组 | expressed in E. coli |
| 测定 | ≥90% (SDS-PAGE) |
| 形式 | liquid |
| 分子量 | 35.5 kDa (339 aa, 1-319 aa + His Tag.) |
| 包装 | pkg of 50 μg |
| 浓度 | 0.5 mg/mL |
| UniProt登记号 | P32322 |
| 运输 | dry ice |
| 储存温度 | −70℃ |
| Gene Information | human ... PYCR1(5831) |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
