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RIZ1 (2-200) GST tag human

品牌
Sigma-Aldrich
货号
SRP6588
规格纯度
recombinant, expressed in E. coli, ≥95% (SDS-PAGE)
参考价格
2350.14 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
RIZ1 (2-200) GST tag human
Retinoblastoma Protein-interacting Zinc Finger Protein
PR domain zinc finger protein 2
KMT8
PRDM2
产品介绍:

产品说明

一般描述

Retinoblastoma protein-interacting zinc finger protein 1 (RIZ1), also known as PRDM2, is a SAM-dependent histone methyltransferase that specifically methylates histone H3 on lysine 9. RIZ1 contains 8 zinc-finger motifs and 1 PR domain. The RIZ gene encodes two different proteins, RIZ1 and RIZ2. RIZ1 is a tumor suppressor that can arrest the cell cycle and induce apoptosis. RIZ2 however, is a proto-oncoprotein lacking the N-terminal PR domain containing the methyltransferase activity. When RIZ1 is silenced or mutated, the reduced methyltransferase activity can lead to inheritable changes in chromatin methylation and gene expression patterns.

外形

50 mM Tris, pH 7.5, containing 150 mM sodium chloride and 20% glycerol.

基本信息

NACRESNA.32

产品性质

生物来源human
重组expressed in E. coli
测定≥95% (SDS-PAGE)
形式liquid
分子量 49.5 kDa (2-200 aa + NT GST Tag)
包装pkg of 100 μg
pkg of 50 μg
UniProt登记号Q13029
运输dry ice
储存温度−70℃
Gene Informationhuman ... PRDM2(7799)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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