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RNA Polymerase II, RPB10 subunit, GST tagged human

品牌
Sigma-Aldrich
货号
SRP2118
规格纯度
recombinant, expressed in E. coli, ≥85% (SDS-PAGE)
参考价格
5245.91 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
RNA Polymerase II, RPB10 subunit, GST tagged human
RPB10
RPABC5
hsRPB10b
RPB10beta
RPB7.6
hRPB7.6
RBP10
产品介绍:

产品说明

生化/生理作用

The RNA polymerase subunit RPB10 displays a high level of conservation across archaea and eukarya and is required for cell viability in yeast. It is a zinc-binding protein with an atypical CX2CXnCC metal binding motif. RPB10 participates in protein-protein interactions with additional components of the polymerase holoenzyme. Experimentally, the binding of RPB10 to an RPB3-RPB11 (or RPAC40-RPAC19 in RNAPI/III) heterodimer is well characterized and persists in both eukaryal and archaeal RNAPs. Binding of RPB10 to this a2-like heterodimer through zinc-mediated hemi-coordination suggests an early role in holoenzyme assembly since the formation of the α2-complex is the first step in the assembly of the prokaryotic RNAPs.

外形

Clear and colorless frozen liquid solution

制备说明

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.

基本信息

NACRESNA.26

产品性质

生物来源human
重组expressed in E. coli
测定≥85% (SDS-PAGE)
形式frozen liquid
分子量 ~33.6 kDa
包装pkg of 10 μg
储存条件avoid repeated freeze/thaw cycles
浓度300 μg/mL
颜色clear colorless
NCBI登记号NM_021128
UniProt登记号P62875
运输dry ice
储存温度−70℃
Gene Informationhuman ... POLR2L(5441)

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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