RO5256390

产品名称：

1043495-96-0
RO5256390
(S)-4-((S)-2-phenyl-butyl)-4,5-dihydro-oxazol-2-ylamine

产品介绍：

产品说明

生化/生理作用

RO5256390 is an agonist of Trace amine-associated receptor 1 (TAAR1), a GPCR primarily found in the brain, expressed in areas where the major monoamine amine transmitters (DA and NE) are also present. RO5256390 is a selective TAAR1 agonist shown to be a negative regulator of dopamine transmission. It has antipsychotic activity in models of schizophrenia, reduces cocaine′s reinforcng effects, and blocks binge-eating disorder.

基本信息

经验(实验)分子式	C₁₃H₁₈N₂O
分子量	218.29
MDL编号	MFCD28405494

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
旋光性	[α]/D 14 to 19°, c = 1 in methanol
颜色	white to beige
溶解性	DMSO: 10 mg/mL, clear
储存温度	2-8℃
SMILES string	CC[C@@H](C[C@H]1COC(N)=N1)C2=CC=CC=C2

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable