Salsalate

产品名称：

552-94-3
Salsalate
2-Hydroxybenzoic acid 2-carboxyphenyl ester
salicyloxysalicylic acid
disalicylic acid
2-(2-Hydroxybenzoyl)oxybenzoic acid
Salicylsalicylic acid

产品介绍：

产品说明

应用

Salsalate was used to study the effect on palmitate-induced insulin resistance and hepatic steatosis in obese rats.

包装

50, 250 mg in glass bottle

生化/生理作用

Salsalate is a nonsteroidal anti-inflammatory drug (NSAID), a nonacetylated salicylate with no more problems of gastrointestinal bleeding than placebo. It inhibits synthesis and release of prostaglandins through the inactivation of cyclooxygenase-1 (COX-1) and COX-2. Salsalate is currently being investigated as a treatment for Type 2 diabetes with possible use to prevent the disease in people at risk. It reduces blood glucose concentrations in patients with type 2 diabetes, as well as in insulin-resistant patients without diabetes.

基本信息

经验(实验)分子式	C₁₄H₁₀O₅
分子量	258.23
EC 号	209-027-4
MDL编号	MFCD00020252
PubChem化学物质编号	329825134
NACRES	NA.77

产品性质

测定	≥98% (HPLC)
形式	powder
颜色	white to tan
溶解性	DMSO: ≥15 mg/mL
储存温度	room temp
SMILES string	OC(=O)c1ccccc1OC(=O)c2ccccc2O
InChI	1S/C14H10O5/c15-11-7-3-1-5-9(11)14(18)19-12-8-4-2-6-10(12)13(16)17/h1-8,15H,(H,16,17)
InChI key	WVYADZUPLLSGPU-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H302 - H400
预防措施声明	P273 - P301 + P312 + P330
危险分类	Acute Tox. 4 Oral - Aquatic Acute 1
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable