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Saxagliptin Hydrate

品牌
Sigma-Aldrich
CAS
945667-22-1
货号
SML3046
规格纯度
≥98% (HPLC)
参考价格
841.96 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
945667-22-1
Saxagliptin Hydrate
BMS477118-11
BMS-477118
(S)-3-Hydroxyadamantylglycine-L-cis-4,5-methanoprolinenitrile hydrate
BMS 477118
BMS-477118-11
BMS 477118-11
BMS477118
产品介绍:

产品说明

生化/生理作用

Saxagliptin (BMS-477118) is an orally active, highly potent and long-acting dipeptidyl peptidase IV inhibitor (human DPP-IV Ki = 0.9 nM; plasma DDP-IV inhibition = 87% 0.5-4h post 4 μmol/kg po. in normal rats) with therapeutic efficacy against type 2 diabetes in vivo (plasma glucose clearance = 28/43/61% post 0.3/1.0/3.0 μmol/kg po. in Zucker fa/fa rats).

基本信息

经验(实验)分子式C18H25N3O2 · H2O
分子量333.43

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 white to beige
溶解性DMSO: 2 mg/mL, clear
储存温度−20℃
SMILES stringOC12CC([C@@H](C(N3[C@@H](C[C@]4([C@@]3(C4)[H])[H])C#N)=O)N)(CC(C5)C2)CC5C1.O

Sigma-Aldrich

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