产品说明
一般描述
SETMAR or SET domain and mariner transposase fusion gene is a nonhomologous end-joining repair protein that regulates genomic integration of exogenous DNA by opening chromatin and facilitating joining of DNA ends. SETMAR has histone methyltransferase activity and methylates ′Lys-4′ and ′Lys-36′ of histone H3. SETMAR also has DNA nicking activity and may play a role in DNA repair. Human Pso4 forms a stable complex with SETMAR that regulates Metnase function in DNA repair. SETMAR has sequence-specific DNA-binding activity and recognizes the 19-mer core of the 5′-terminal inverted repeats (TIRs) of the Hsmar1 element.
外形
Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
制备说明
After opening, aliquot into smaller quantities and store at -70 ℃. Avoid repeating handling and multiple freeze/thaw cycles.
基本信息
| NACRES | NA.32 |
产品性质
| 重组 | expressed in baculovirus infected Sf9 cells |
| 测定 | ≥70% (SDS-PAGE) |
| 形式 | buffered aqueous glycerol solution |
| 分子量 | 66-69 kDa |
| NCBI登记号 | BC011635 |
| 运输 | dry ice |
| 储存温度 | −70℃ |
| Gene Information | human ... SETMAR(6419) |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
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