产品说明
生化/生理作用
Sophocarpine is a natural product found to have anti-inflammatory, anti-cancer, and antiviral activity. Sophocarpine was active in an mouse xenograft model. It inhibited growth of head and neck squamous cell carcinomas by downregulation of miR-21 expression. Sophocarpine was also shown to protecs mice from a form of hepatitis by inhibiting the IFNg/STAT1 pathway.
基本信息
经验(实验)分子式 | C15H22N2O |
分子量 | 246.35 |
MDL编号 | MFCD00274555 |
产品性质
生物来源 | Sophora alopecuroides |
测定 | ≥95% (HPLC) |
形式 | powder |
旋光性 | [α]/D -26 to -35°, c = 0.5 in ethanol |
颜色 | white to beige |
溶解性 | DMSO: 2 mg/mL, clear |
储存温度 | −20℃ |
InChI | 1S/C15H22N2O.BrH/c18-14-7-1-6-13-12-5-3-9-16-8-2-4-11(15(12)16)10-17(13)14;/h1,7,11-13,15H,2-6,8-10H2;1H/t11-,12+,13+,15-;/m0./s1 |
InChI key | NBBQEIQEBNYSFK-PUILLJIJSA-N |
安全信息
象形图 | |
警示用语: | Danger |
危险声明 | H301 |
预防措施声明 | P264 - P270 - P301 + P310 + P330 - P405 - P501 |
危险分类 | Acute Tox. 3 Oral |
储存分类代码 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich