产品说明
特点和优势
SPDP-dPEG36-NHS ester is an amphiphilic, water-soluble PEGylation reagent that is designed to crosslink amines and free thiols. SPDP (also referred to as orthopyridyl disulfide, or OPSS) reacts with sulfhydryl groups to form disulfide bonds. The N-hydroxysuccinimidyl (NHS) ester reacts with free amines to form amide bonds. The single molecular weight, discrete chain length polyethylene glycol (dPEG) chain is 115 atoms (137.8 Å) long. SPDP-dPEG36-NHS ester is used like SPDP and its related hydrophobic products. However, the water-soluble dPEG product prevents hydrophobicity-triggered precipitation of compounds to which it is conjugated. SPDP-dPEG36-NHS ester is a monodisperse equivalent of the polymeric PEG1500.
法律信息
Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681
dPEG is a registered trademark of Quanta BioDesign
基本信息
| 经验(实验)分子式 | C87H161N3O41S2 |
| 分子量 | 1969.33 |
| MDL编号 | MFCD21363283 |
产品性质
| 测定 | >95% (HPLC) |
| 形式 | solid or viscous liquid |
| reaction suitability | reaction type: Pegylations |
| 聚合物结构设计 | shape: linear functionality: heterobifunctional |
| 运输 | ambient |
| 储存温度 | −20℃ |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
