(<I>R</I>)-(-)-2-氟-α-甲基-4-联苯乙酸

产品名称：

51543-40-9
Tarenflurbil
(R)-(-)-2-Fluoro-α-methyl-4-biphenylacetic acid
(-)-(R)-Flurbiprofen
(2R)-2-(3-Fluoro-4-phenylphenyl)propanoic acid
Flurizan
(R)-2-Flurbiprofen
αR)-2-Fluoro-α-methyl[1,1′-biphenyl]-4-acetic acid
(R)-Flurbiprofen
R-flurbiprofen
(R)-(-)-2-氟-α-甲基-4-联苯乙酸
(R)-2-氟比洛芬
氟比洛芬

产品介绍：

产品说明

生化/生理作用

Tarenflurbil (or R-flurbiprofen) is an R enantiomer of racemic NSAID flurbiprofen that does not inhibit either cyclooxygenase 1 (COX-1) or cyclooxygenase 2 (COX-2). Tarenflurbil potently reduces levels of beta amyloid in human cells through direct inhibition of γ-secretase.

基本信息

线性分子式	C₆H₅C₆H₃(F)CH(CH₃)CO₂H
分子量	244.26
MDL编号	MFCD00869714

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 2 mg/mL, clear
储存温度	2-8℃
SMILES string	C[C@@H](C(O)=O)c1ccc(c(F)c1)-c2ccccc2
InChI	1S/C15H13FO2/c1-10(15(17)18)12-7-8-13(14(16)9-12)11-5-3-2-4-6-11/h2-10H,1H3,(H,17,18)/t10-/m1/s1
InChI key	SYTBZMRGLBWNTM-SNVBAGLBSA-N

安全信息

象形图
警示用语：	Danger
危险声明	H301 + H311 - H317 - H361d
预防措施声明	P201 - P280 - P301 + P310 + P330 - P302 + P352 + P312
危险分类	Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Repr. 2 - Skin Sens. 1B
储存分类代码	6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable