Tavaborole

产品名称：

174671-46-6
Tavaborole
AN-2690
1,3-Dihydro-5-fluoro-1-hydroxy-2,1-benzoxaborole
5-Fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole
AN2690

产品介绍：

产品说明

一般描述

Tavaborole is a boron-based pharmaceutical agent. It has broad-spectrum oxaborole antifungal activity. Due to its low molecular weight, it facilitates maximal nail plate penetration than its predecessors.

包装

10, 50 mg in glass bottle

生化/生理作用

Tavaborole (AN2690) is a potent antifungal that targets the post-transfer editing site of leucyl-tRNA synthetase (LeuRS). Tavaborole forms a covalent adduct with the 3′ adenosine of tRNA(leu) at the editing site of fungal, but not bacterial LeuRS, locking the enzyme in an inactive conformation. Tavaborole was recently approved for the treatment of onychomycosis of the toenail in adults.

基本信息

经验(实验)分子式	C₇H₆BFO₂
分子量	151.93
NACRES	NA.77

产品性质

质量水平	100
测定	≥95% (HPLC)
形式	powder
储存条件	desiccated
颜色	white to beige
溶解性	DMSO: 20 mg/mL, clear
储存温度	−20℃

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable