Tegaserod maleate

产品名称：

189188-57-6
Tegaserod maleate
2-[(5-Methoxy-1H-indol-3-yl)methylene]-N-pentyl-hydrazinecarboximidamide maleate

产品介绍：

产品说明

应用

Tegaserod maleate has been used to study its cytotoxic effects on human astrocytes and to study its effects as an anti-glioblastoma agent.

包装

10, 50 mg in glass bottle

生化/生理作用

It stimulates neurotransmitter release from enteric nerves and regularizes gastrointestinal function. Tegaserod has been used to treat irritable bowel syndrome associated with constipation and chronic constipation.
Tegaserod is a potent full agonist at serotonin 5-HT4 receptors with an EC₅₀ of 7 nM.

基本信息

经验(实验)分子式	C₁₆H₂₃N₅O · C₄H₄O₄
分子量	417.46
MDL编号	MFCD09028009
PubChem化学物质编号	329825925
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 20 mg/mL, clear
储存温度	2-8℃
SMILES string	N=C(NCCCCC)N/N=C/C1=CNC2=C1C=C(OC)C=C2.OC(/C=C\C(O)=O)=O
InChI	1S/C16H23N5O.C4H4O4/c1-3-4-5-8-18-16(17)21-20-11-12-10-19-15-7-6-13(22-2)9-14(12)15;5-3(6)1-2-4(7)8/h6-7,9-11,19H,3-5,8H2,1-2H3,(H3,17,18,21);1-2H,(H,5,6)(H,7,8)/b20-11+;2-1-
InChI key	CPDDZSSEAVLMRY-FEQFWAPWSA-N
Gene Information	human ... HTR4(3360)

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable