产品说明
包装
10, 50 mg in glass bottle
生化/生理作用
Tipiracil is an inhibitor of thymidine phosphorylase. Tipiracil is used in combination with trifluridine as TAS-102 for the treatment of refractory metastatic colorectal cancer. Tipiracil increases the bioavailability of trifluridine by blocking the enzyme that would otherwise protect the tumors by metabolizing trifluridine.
基本信息
| 经验(实验)分子式 | C9H11ClN4O2 · HCl |
| 分子量 | 279.12 |
| MDL编号 | MFCD01571384 |
| PubChem化学物质编号 | 329825960 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 储存条件 | desiccated |
| 颜色 | white to beige |
| 溶解性 | H2O: 5 mg/mL, clear (warmed) |
| 储存温度 | 2-8℃ |
| SMILES string | [H]Cl.ClC1=C(CN2C(CCC2)=N)NC(NC1=O)=O |
| InChI | 1S/C9H11ClN4O2.ClH/c10-7-5(12-9(16)13-8(7)15)4-14-3-1-2-6(14)11;/h11H,1-4H2,(H2,12,13,15,16);1H |
| InChI key | KGHYQYACJRXCAT-UHFFFAOYSA-N |
| Gene Information | human ... TYMP(1890) |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
