Tipiracil hydrochloride

产品名称：

183204-72-0
Tipiracil hydrochloride
5-Chloro-6-[(2-imino-1-pyrrolidinyl)methyl]-2,4(1H,3H)-pyrimidinedione hydrochloride
TPI hydrochloride

产品介绍：

产品说明

包装

10, 50 mg in glass bottle

生化/生理作用

Tipiracil is an inhibitor of thymidine phosphorylase. Tipiracil is used in combination with trifluridine as TAS-102 for the treatment of refractory metastatic colorectal cancer. Tipiracil increases the bioavailability of trifluridine by blocking the enzyme that would otherwise protect the tumors by metabolizing trifluridine.

基本信息

经验(实验)分子式	C₉H₁₁ClN₄O₂ · HCl
分子量	279.12
MDL编号	MFCD01571384
PubChem化学物质编号	329825960
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
储存条件	desiccated
颜色	white to beige
溶解性	H₂O: 5 mg/mL, clear (warmed)
储存温度	2-8℃
SMILES string	[H]Cl.ClC1=C(CN2C(CCC2)=N)NC(NC1=O)=O
InChI	1S/C9H11ClN4O2.ClH/c10-7-5(12-9(16)13-8(7)15)4-14-3-1-2-6(14)11;/h11H,1-4H2,(H2,12,13,15,16);1H
InChI key	KGHYQYACJRXCAT-UHFFFAOYSA-N
Gene Information	human ... TYMP(1890)

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable