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TNFR1/CD120a/TNFRSF1A human

品牌
Sigma-Aldrich
货号
SRP6389
规格纯度
recombinant, expressed in HEK 293 cells, ≥92% (SDS-PAGE)
参考价格
3487.6 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
TNFR1/CD120a/TNFRSF1A human
p60
TNF-R-I
TNFR60
TNFAR
TNF-R55
TNF-R
p55
TNFR55
TBP1
FPF
产品介绍:

产品说明

一般描述

Tumor necrosis factor receptor 1 (TNF-R1) also known as Tumor necrosis factor receptor superfamily member 1A (TNFRSF1A), TNFAR, CD antigen CD120a, belongs to the tumor necrosis factor receptor superfamily. TNF-R1 contains one death domain and four TNFR-Cys repeats. TNF-R1 is the receptor of TNFSF2 / TNF-α and homotrimeric TNFSF1 / lymphotoxin - α. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. TNF-R1 contributes to the induction of non - cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase. Defects in TNFRSF1A are the cause of familial Hibernian fever (FHF).

外形

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization.

重悬

Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/mL. Do not vortex. This solution can be stored at 2-8℃ for up to 1 month. For extended storage, it is recommended to store at -20℃.

产品性质

生物来源human
重组expressed in HEK 293 cells
标签6-His tagged (C-terminus)
测定≥92% (SDS-PAGE)
形式lyophilized
分子量calculated mol wt 22 kDa
observed mol wt 30-35 kDa (DTT-reduced. Protein migrates due to different glycosylation. Ile 22 is the predicted N-terminus.)
包装pkg of 10 μg
pkg of 50 μg
杂质<1 EU/μg endotoxin (LAL test)
UniProt登记号P19438
运输wet ice
储存温度−20℃
Gene Informationhuman ... TNFRSF1A(7132)

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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