Topiroxostat

产品名称：

577778-58-6
Topiroxostat
FYX 051
FYX-051
4-[3-(4-Pyridinyl)-1H-1,2,4-triazol-5-yl]-2-pyridinecarbonitrile
5-(2-Cyano-4-pyridyl)-3-(4-pyridyl)-1,2,4-triazole
4-[5-(pyridin-4-yl)-1H-1,2,4-triazol-3-yl]pyridine-2-carbonitrile

产品介绍：

产品说明

生化/生理作用

Topiroxostat (FYX-051) is an orally active and potent inhibitor of xanthine oxidoreductase (XOR). It appears that inhibition of XOR by topiroxostat is due to the formation a covalent linkage to molybdenum via oxygen in the hydroxylation reaction intermediate. Also, topiroxostat displayed a potent, non-covalent inhibition of XOR. It is approved for the treatment of gout and hyperuricemia in Japan.

基本信息

经验(实验)分子式	C₁₃H₈N₆
分子量	248.24
MDL编号	MFCD17167057

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 2 mg/mL, clear (warmed)
储存温度	2-8℃
SMILES string	N#CC1=NC=CC(C2=NNC(C3=CC=NC=C3)=N2)=C1

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable