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ULBP2 human

品牌
Sigma-Aldrich
货号
SRP6348
规格纯度
recombinant, expressed in E. coli, ≥85% (SDS-PAGE)
参考价格
6021.17 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
-+
产品名称:
ULBP2 human
N2DL2
NKG2D ligand 2
RAET1H
产品介绍:

产品说明

一般描述

ULBP2, also known as NKG2D ligand 2, belongs to the MHC class I family. This protein is ligand for the NKG2D receptor, together with at least ULBP1 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked the interaction with the NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. UL16 also causes ULBP2 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface. Recombinant human ULBP2 protein, fused to His-tag at N-terminus, was expressed in E.coli.

外形

1 mg/mL in 20 mM Tris-HCl buffer (pH 8.0) containing 0.2 M NaCl, 30% glycerol, 2 M Urea and 2 mM DTT.

基本信息

NACRESNA.32

产品性质

生物来源human
重组expressed in E. coli
测定≥85% (SDS-PAGE)
形式liquid
分子量 24.3 kDa (216 aa, 26-216 aa + His Tag)
包装pkg of 100 μg
浓度1 mg/mL
UniProt登记号Q9BZM5 
运输dry ice
储存温度−70℃
Gene Informationhuman ... ULBP2(80328)

安全信息

象形图GHS07
警示用语:Warning
危险声明H319
预防措施声明P264 - P280 - P305 + P351 + P338 - P337 + P313
危险分类Eye Irrit. 2
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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