产品说明
一般描述
ULK4, or Unc-51-like kinase 4, is a Ser/Thr protein kinase that is a member of the APG1/unc-51/ULK1 subfamily. ULK4 contains five HEAT repeats and a catalytic kinase domain. The ULK4 gene is conserved in many species including chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, A.thaliana, and rice. ULK4 has been implicated as a gene involved in the development of hydrocephalus. This neurologic disorder in animal models is being used to elucidate factors responsible for the excessive accumulation of cerebrospinal fluid in hydrocephalic humans.
外形
Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
制备说明
After opening, aliquot into smaller quantities and store at -70 ℃. Avoid repeating handling and multiple freeze/thaw cycles.
基本信息
NACRES | NA.32 |
产品性质
生物来源 | human |
重组 | expressed in baculovirus infected Sf9 cells |
测定 | ≥70% (SDS-PAGE) |
形式 | buffered aqueous glycerol solution |
分子量 | ~97 kDa |
NCBI登记号 | NM_017886 |
application(s) | cell analysis |
运输 | dry ice |
储存温度 | −70℃ |
Gene Information | human ... ULK4(54986) |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich