产品说明
一般描述
VEGI (Vascular Endothelial Growth Inhibitor) is a member of the tumor necrosis factor family. VEGI is predominantly an endothelial cell-specific gene, and recombinant VEGI is a potent inhibitor of endothelial cell proliferation, angiogenesis and tumor growth. VEGI exerts two activities of endothelial cells: early Gl arrest of G0/G1-cells responding to growth stimuli, and programmed cell death. VEGI is also able to regulate the expression of several important genes involved in angiogenesis. Human VEGF is a 21.8 kDa homodimeric protein consisting of 192 amino acid polypeptide chains.
外形
Lyophilized from a solution containing 0.5 M NaCl, 50 mM Tris-HCl, pH 7.5.
重悬
Reconstitute in water to a concentration of 0.1–1.0 mg/mL. This solution can then be diluted into other aqueous buffers.
Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
基本信息
NACRES | NA.32 |
产品性质
生物来源 | human |
重组 | expressed in E. coli |
测定 | ≥95% (HPLC) ≥95% (SDS-PAGE) |
形式 | lyophilized |
分子量 | ~21.8 kDa |
包装 | pkg of 10 μg |
储存条件 | avoid repeated freeze/thaw cycles |
杂质 | endotoxin, tested |
NCBI登记号 | AAR98573 |
UniProt登记号 | O95150 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... TNFSF15(41019336) |
Sigma-Aldrich