Viloxazine hydrochloride

产品名称：

35604-67-2
Viloxazine hydrochloride
2-[(2-Ethoxyphenoxy)methyl]morpholinium chloride
I.C.I. 58,834 HCl
ICI 58,834 HCl
Viloxazine HCl
2-(o-Ethoxyphenoxymethyl)morpholine hydrochloride
SPN-812
2-((2-Ethoxyphenoxy)methyl)morpholine hydrochloride
rac Viloxazine HCl
1. 2-(2-Ethoxyphenoxymethyl-2,3,5,6-tetrahydro-1,4-oxazine hydrochloride salt
rac Viloxazine hydrochloride

产品介绍：

产品说明

生化/生理作用

Viloxazine (ICI 58,834) is an orally active serotonin norepinephrine modulating agent (SNMA) originally reported as a norepinephrine reuptake inhibitor (NRI) with antidepressant (ED10 from 0.3-1 mg/kg p.o. against reserpine-induced hypothermia in mice), while exhibiting less sedative efficacy (locomotor activity reduction ED10 from 3-10 mg/kg p.o. in mice) and no monoamine oxidase inhibitory potency. Viloxazine shows 5-HT2B antagonist and 5-HT2C agonist activity in vitro and increases extracellular 5-HT levels in the prefrontal cortex (PFC) in vivo, a brain area implicated in Attention deficit hyperactivity disorder (ADHD).

基本信息

经验(实验)分子式	C₁₃H₁₉NO₃ · HCl
分子量	273.76
MDL编号	MFCD00661100

产品性质

质量水平	100
测定	≥95% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 2 mg/mL, clear
储存温度	2-8℃
SMILES string	CCOC1=C(OCC2OCCNC2)C=CC=C1.Cl

安全信息

象形图
警示用语：	Warning
危险声明	H302
预防措施声明	P264 - P270 - P301 + P312 - P501
危险分类	Acute Tox. 4 Oral
储存分类代码	11 - Combustible Solids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable