产品说明
一般描述
Yu Borylation Ligand, also referred to as 2,4-dimethoxyquinoline, has been developed by Professor Jin-Quan Yu and coworkers. 2,4-dimethoxyquinoline can be prepared by reacting 2,4-dichloroquinoline with sodium methoxide.
应用
The Yu Borylation Ligand in tandem with bis(pinacolato)diboron (Aldrich 473294) under palladium catalysis can promote direct borylation of C(sp3)-H bonds. Yu and coworkers have displayed this on both alanine-derived amides and cyclopropanes with directing group assistance from the Yu-Wasa Auxiliary (Aldrich 791806).
Yu Borylation Ligand (2,4-Dimethoxyquinoline) may be used as a starting reagent in the synthesis of 2,4 -dimethoxy-3-(3methylbut-2-enyl)quinoline and 4-methoxy-1H-quinolin-2-one. It may also be used in the preparation of isoprenyl derivatives.
包装
250 mg in glass bottle
其他说明
Ligand-Promoted Borylation of C(sp3)-H Bonds with Palladium(II) Catalysts
基本信息
经验(实验)分子式 | C11H11NO2 |
分子量 | 189.21 |
MDL编号 | MFCD27950422 |
PubChem化学物质编号 | 329772696 |
NACRES | NA.22 |
产品性质
质量水平 | 100 |
测定 | ≥95% |
形式 | powder |
reaction suitability | reagent type: ligand reaction type: C-H Activation |
SMILES string | COC1=CC(OC)=NC2=CC=CC=C21 |
InChI | 1S/C11H11NO2/c1-13-10-7-11(14-2)12-9-6-4-3-5-8(9)10/h3-7H,1-2H3 |
InChI key | XSZBLRGKCBUWRJ-UHFFFAOYSA-N |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H302 - H315 - H319 - H335 |
预防措施声明 | P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338 |
危险分类 | Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
靶器官 | Respiratory system |
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |