产品说明
一般描述
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
生化/生理作用
唑来膦酸(唑来膦酸盐)是一种双膦酸盐骨吸收抑制剂,是基焦磷酸(FPP)合成酶的抑制剂,其会导致破骨细胞活性的下游抑制并减少骨吸收和转换。它已被用于治疗绝经后的骨质疏松症,佩吉特病、高钙血症,并结合癌症化疗以治疗已经扩散到骨骼的癌症引起的骨损伤。
包装
Unit quantity: 15 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
其他说明
Sales restrictions may apply.
基本信息
经验(实验)分子式 | C5H10N2O7P2·H2O |
分子量 | 290.10 |
MDL编号 | MFCD08448695 |
产品性质
等级 | pharmaceutical primary standard |
储存温度 | 2-8℃ |
SMILES string | O.OC(Cn1ccnc1)(P(O)(O)=O)P(O)(O)=O |
InChI | 1S/C5H10N2O7P2.H2O/c8-5(15(9,10)11,16(12,13)14)3-7-2-1-6-4-7;/h1-2,4,8H,3H2,(H2,9,10,11)(H2,12,13,14);1H2 |
InChI key | FUXFIVRTGHOMSO-UHFFFAOYSA-N |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H315 - H319 - H335 |
预防措施声明 | P261 - P264 - P280 - P280 - P304 + P340 + P312 - P337 + P313 |
危险分类 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
靶器官 | Respiratory system |
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |