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Imiquimod-CAS 99011-02-6-Calbiochem

品牌
Sigma-Aldrich
CAS
99011-02-6
货号
401020
规格纯度
An imidazoquinoline compound that acts as a potent immunomodulator and displays anti-angiogenic, anti-viral and anti-inflammatory properties.
参考价格
3378.28 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
99011-02-6
Imiquimod-CAS 99011-02-6-Calbiochem
1-(2-Methylpropyl)-1H-imidazole[4,5-c]quinoline-4-amine
产品介绍:

产品说明

一般描述

An imidazoquinoline compound that acts as a potent immunomodulator and displays anti-angiogenic, anti-viral and anti-inflammatory properties. Reported to bind to the cell surface receptor, TLR7 (toll-like receptor 7), and induce the secretion of several pro-inflammatory cytokines and chemokines both in vitro and in vivo.

包装

250 mg in Plastic ampoule
Packaged under inert gas

生化/生理作用

Primary Target
TLR7 (toll-like receptor 7)
Product does not compete with ATP.
Reversible: no
Cell permeable: no

警告

Toxicity: Toxic (F)

制备说明

warming to 60°C is required for complete solubilization.

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Upon thawing, warming may be required to resolubilize precipitated product.

其他说明

Majewski, S., et al. 2005. Int. J. Dermatol.44, 14.
Gibson, S.J., et al. 2002. Cell. Immunol.218, 74.
Hemmi, H., et al. 2002. Nat. Immunol.3, 196.
Megyeri, K., et al. 1995. Mol. Cell. Biol.15, 2207.
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C14H16N4
分子量240.30
MDL编号MFCD00866946

产品性质

质量水平100
测定≥98% (HPLC)
形式solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
protect from light
颜色 white
溶解性DMSO: 3 mg/mL
运输ambient
储存温度2-8℃
InChI1S/C14H16N4/c1-9(2)7-18-8-16-12-13(18)10-5-3-4-6-11(10)17-14(12)15/h3-6,8-9H,7H2,1-2H3,(H2,15,17)
InChI keyDOUYETYNHWVLEO-UHFFFAOYSA-N

安全信息

象形图GHS06
警示用语:Danger
危险声明H301 - H315 - H319
预防措施声明P264 - P270 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2
储存分类代码6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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