产品说明
应用
4,6-Dimethyl-2-(methylsulfinyl)-3-nitropyridine is a sulfoxide-containing fragment for covalent ligand discovery via cysteine labeling as demonstrated by Zamboldo and coworkers. Fragment electrophiles are useful in chemoproteomic and ligandability studies for both traditionally druggable proteins as well as ″undruggable,″ or difficult-to-target, proteins.
Related useful products may include cysteine fragment KB02 (912131), IA alkyne (924237), IA 5-TAMRA (925020), desthiobiotin iodoacetamide (923826), or biotin iodoacetamide (B2059).
其他说明
2-Sulfonylpyridines as Tunable, Cysteine-Reactive Electrophiles
基本信息
| 经验(实验)分子式 | C8H10N2O3S |
| 分子量 | 214.24 |
产品性质
| reaction suitability | reagent type: chemical modification reagent |
| 质量水平 | 100 |
| 储存温度 | 2-8℃ |
Sigma-Aldrich
m.cnreagent.com
