产品说明
一般描述
CBX8 is a polycomb group protein that associates with TIP60 and MLL-AF9. It also forms a part of the PRC1 complexes. It regulates fibroblast proliferation and cell survival. Studies have reported that CBX8 is required for MLL-AF9-induced transcription and leukemogenesis.
Rabbit Anti-CBX8 antibody recognizes canine, bovine, human, mouse, rat, and zebrafish CBX8.
免疫原
Synthetic peptide directed towards the C terminal region of human CBX8
应用
Rabbit Anti-CBX8 antibody is suitable for western blot applications at a concentration of 2.5 μg/ml.
生化/生理作用
CBX8 is one of the proteins homolog to the Polycomb group (PcG) proteins. They assemble to form large multiprotein complexes involved in gene silencing. Evidence suggests that PcG complexes are heterogeneous with respect to both protein composition and specific function.
序列
Synthetic peptide located within the following region: ARILGDPEEESWSPSLTNLEKVVVTDVTSNFLTVTIKESNTDQGFFKEKR
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 43 kDa |
| species reactivity | dog, rabbit, bovine, human, mouse, rat, guinea pig, horse |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI登记号 | NP_065700 |
| UniProt登记号 | Q9HC52 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... CBX8(57332) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
