产品说明
一般描述
CLIC1 codes for an intracellular chloride ion channel protein. Studies have reported that oxidized CLIC1 dimers can form chloride ion channels in synthetic vesicles and bilayers. In the absence of detergents, CLIC1 can spontaneously insert into preformed membranes.
Rabbit Anti-CLIC1 antibody recognizes rabbit, canine, zebrafish, bovine, human, mouse, rat, and pig CLIC1.
免疫原
Synthetic peptide directed towards the N terminal region of human CLIC1
应用
Rabbit Anti-CLIC1 antibody is suitable for western blot applications at a concentration of 1.25 μg/ml and for IHC at 4-8 μg/ml.
生化/生理作用
Chloride intracellular channel 1 is a member of the p64 family, a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. CLIon Channel1 encodes a protein that localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity.
序列
Synthetic peptide located within the following region: GQLPFLLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIF
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 27 kDa |
| species reactivity | bovine, goat, horse, dog, rat, rabbit, guinea pig, human, mouse |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI登记号 | NP_001279 |
| UniProt登记号 | Q502X1 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... CLIC1(1192) |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
