产品说明
一般描述
FGFR1 oncogene partner is a protein encoded by the FGFR1OP gene in humans. The fibroblast growth factor receptor 1 (FGFR1) oncogene partner called FOP is a centrosomal protein that is involved in the anchoring of microtubules (MTS) to subcellular structures.
免疫原
Synthetic peptide directed towards the N terminal region of human FGFR1OP
应用
Anti-FGFR1OP (AB1) antibody produced in rabbit is suitable for western blotting at a concentration of 1μg/mL.
生化/生理作用
FGFR1OP (FGFR1 oncogene partner)/FOP encodes a hydrophilic centrosomal protein predominantly expressd in heart, liver, muscle, kidney, intestine, colon, adrenal gland, prostate, testis and pancreas. It interacts with EB1 and facilitates the microtubules anchoring to the centrosomes. It plays an important role in normal proliferation and differentiation of the erythroid lineage. Attenuation of Fgfr1 disrupts cochlear hair cell formation.
序列
Synthetic peptide located within the following region: FLQFFNLDFTLAVFQPETSTLQGLEGRENLARDLGIIEAEGTVGGPLLLE
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
偶联物 | unconjugated |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
分子量 | 41 kDa |
species reactivity | human |
浓度 | 0.5 mg - 1 mg/mL |
technique(s) | western blot: suitable |
NCBI登记号 | NP_919410 |
UniProt登记号 | O95684 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... FGFR1OP(11116) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich