产品说明
免疫原
Synthetic peptide directed towards the N terminal region of human NR1I3
应用
Anti-NR1I3 (AB4) antibody produced in rabbit is suitable for western blotting at a concentration of 1.25μg/ml and for immunohistochemistry of paraffin-embedded tissue sections at a concentration of 4-8μg/ml.
生化/生理作用
Nuclear receptor subfamily 1, group I, member 3 (NR1I3), also known as constitutive androstane receptor (CAR; CAR1) is a nuclear receptor that acts with retinoid X receptor to regulate xenobiotic and endobiotic metabolism. The ligands for this receptor include steroid hormones, drugs and bilirubin. On binding the ligands, NR1l3 translocates to the nucleus and regulates the transcription of genes involved in drug metabolism, energy homeostasis and cancer development.
序列
Synthetic peptide located within the following region: MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFA
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| MDL编号 | MFCD00802755 |
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 39 kDa |
| species reactivity | pig, human |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI登记号 | NP_001070937 |
| UniProt登记号 | Q5VTW5 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... NR1I3(9970) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
