产品说明
一般描述
Rabbit polyclonal anti-SALF antibody reacts with human, mouse, zebrafish, canine, bovine, and rat stoning-1 clathrin adaptor factors.
Stonins are evolutionarily conserved, clathrin adaptor complex (AP-2mu-related) factors. They may function as cargo-specific sorting adaptors during cellular endocytosis. Stonin 1 (STON1 or SALF) is the human homolog of the Drosophila protein, stoned B.
免疫原
Synthetic peptide directed towards the C terminal region of human SALF
应用
Rabbit polyclonal anti-SALF antibody is used to tag stonin-1 for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques. It is used as a probe to determine the presence and roles of stonin-1 in processes related to cargo-specific sorting in endocytosis.
Rabbit Anti-SALF antibody can be used for western blot application at a concentration of 5μg/ml.
生化/生理作用
The SALF mRNA is an infrequent but naturally occurring co-transcribed product of the neighboring SBLF and ALF genes. This rare transcript encodes a fusion protein composed of greater than 95% each of the individual elements, stoned B-like factor (SBLF) and TFIIA-alpha/beta-like factor (ALF). The significance of this co-transcribed mRNA and the function of its protein product have not yet been determined.
序列
Synthetic peptide located within the following region: NSGDDVSEQDVPDLFDTDNVIVCQYDKIHRSKNKWKFYLKDGVMCFGGRD
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
偶联物 | unconjugated |
抗体形式 | IgG fraction of antiserum |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
分子量 | 132 kDa |
species reactivity | dog, rabbit, bovine, mouse, human, rat, guinea pig |
浓度 | 0.5 mg - 1 mg/mL |
technique(s) | western blot: suitable |
NCBI登记号 | NP_006863 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... SALF(11036) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich