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β-Secretase Inhibitor III-Calbiochem

品牌
Sigma-Aldrich
货号
565780
规格纯度
The β-Secretase Inhibitor III controls the biological activity of β-Secretase. This small molecule/inhibitor is primarily used for Neuroscience applications.
参考价格
2340.22 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
β-Secretase Inhibitor III-Calbiochem
Inhibitor GL189, H-EVNstatineVAEF-NH2
产品介绍:

产品说明

一般描述

A substrate analog inhibitor of β-secretase (BACE) that completely blocks proteolytic activity in solubilized membrane fractions of BACE-transfected MDCK cells at a concentration of 5 µM.
A substrate analog inhibitor of β-secretase (BACE) that completely blocks the proteolytic activity (at 5 µM) in solubilized membrane fractions from BACE transfected MDCK cells.

包装

500 μg in Plastic ampoule
Packaged under inert gas

生化/生理作用

Product does not compete with ATP.
Primary Target
BACE
Reversible: no
Effective concentration: 5 µM completely blocking the proteolytic activity of β-secretase (BACE) in solubilized membrane fractions from BACE transfected MDCK cells
Cell permeable: no

警告

Toxicity: Standard Handling (A)

序列

H-Glu-Val-Asn-Statine-Val-Ala-Glu-Phe-NH₂

外形

Supplied as a trifluoroacetate salt.

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他说明

Capell, A., et al. 2002. J. Biol. Chem.277, 5637.
Tung, J.S., et al. 2002. J. Med. Chem.45, 259.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C44H70N10O14
分子量963.09

产品性质

质量水平100
测定≥95% (HPLC)
形式lyophilized
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
desiccated (hygroscopic)
溶解性DMSO: 1 mg/mL
运输ambient
储存温度−20℃

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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