C5 Lenalidomide

产品名称：

191732-70-4
C5 Lenalidomide
Ligand for PROTAC research
E3 Ligase ligand
3-(5-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione

产品介绍：

产品说明

应用

C5 Lenalidomide is a derivative of the Cereblon (CRBN)-binding ligand lenalidomide, which possesses an amine at the C4 position. C5 Lenalidomide can be used to bind the CRBN E3 ubiquitin ligase in targeted protein degradation research or in the synthesis of protein degraders with a C5 exit vector. Learn more about proteolysis-targeting chimeras (PROTACs) and the building blocks to design them in our Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation

其他说明

Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation

Portal: Building PROTAC^® Degraders for Targeted Protein Degradation

Amino-substituted thalidomide analogs: potent inhibitors of TNF-alpha production

Targeted Protein Degradation by Small Molecules

法律信息

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

基本信息

经验(实验)分子式	C₁₃H₁₃N₃O₃
分子量	259.26
MDL编号	MFCD31692701

产品性质

测定	≥95%
形式	powder
储存温度	2-8℃
SMILES string	NC1=CC=C2C(CN(C3CCC(NC3=O)=O)C2=O)=C1 NC1=CC=C2C(CN(C3CCC(NC3=O)=O)C2=O)=C1

安全信息

象形图
警示用语：	Warning
危险声明	H361d - H373
预防措施声明	P201 - P308 + P313
危险分类	Repr. 2 - STOT RE 2
靶器官	Blood
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable