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Caffeic Acid-CAS 331-39-5-Calbiochem

品牌
Sigma-Aldrich
CAS
331-39-5
货号
205546
规格纯度
A natural dietary compound reported to have anti-carcinogenic and anti-inflammatory properties.
参考价格
1296.97 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
-+
产品名称:
331-39-5
Caffeic Acid-CAS 331-39-5-Calbiochem
3,4-Dihydroxycinnamic acid
产品介绍:

产品说明

一般描述

A cell-permeable natural dietary compound reported to have anti-carcinogenic and anti-inflammatory properties. A selective, non-competitive inhibitor of 5-lipoxygenase (ID50 = 3.7 µM). Inhibits Cu2+-induced LDL oxidation in the initiation phase but acts as a prooxidant in the propagation phase. An effective irreversible inhibitor of glutathione S-transferases and a non-competitive inhibitor of xanthine oxidase.
A natural dietary compound reported to have anti-carcinogenic and anti-inflammatory properties. A cell-permeable, selective, non-competitive inhibitor of 5-lipoxygenase (ID50 = 3.7 µM). Inhibits Cu2+-induced LDL oxidation in the initiation phase but acts as a prooxidant in the propagation phase. An irreversible inhibitor of glutathione S-transferases and a non-competitive inhibitor of xanthine oxidase.

包装

500 mg in Plastic ampoule
Packaged under inert gas

生化/生理作用

Cell permeable: yes
Primary Target
5-lipoxygenase
Product does not compete with ATP.
Reversible: no
Target IC50: 3.7 µM against 5-lipoxygenase

警告

Toxicity: Carcinogenic / Teratogenic (D)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他说明

Yamanaka, N., et al. 1997. FEBS Lett.405, 186.
Chan, W.S., et al. 1995. Anticancer Res.15, 703.
Ploemen, J.H., et al. 1993. Food Chem. Toxicol.31, 475.
Koshihara, Y., et al. 1984. Biochim. Biophys. Acta792, 92.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C9H8O4
分子量180.16
MDL编号MFCD00004392

产品性质

质量水平100
测定≥95% (HPLC)
形式crystalline solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
颜色 tan
溶解性DMSO: 200 mg/mL
ethanol: 50 mg/mL
运输ambient
储存温度2-8℃
InChI1S/C9H8O4/c10-7-3-1-6(5-8(7)11)2-4-9(12)13/h1-5,10-11H,(H,12,13)/b4-2-
InChI keyQAIPRVGONGVQAS-RQOWECAXSA-N

安全信息

象形图GHS08
警示用语:Warning
危险声明H351
预防措施声明P201 - P202 - P280 - P308 + P313 - P405 - P501
危险分类Carc. 2
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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