Carboxylic acid-poly(ethylene glycol)-<i>b</i>-poly(ε-caprolactone)

产品名称：

Carboxylic acid-poly(ethylene glycol)-b-poly(ε-caprolactone)
Carboxylic acid-PEG-PCL
PEG-PCL
PEG-b-PCL
Carboxylic acid PEG-PCL diblock copolymer

产品介绍：

产品说明

应用

Carboxylic acid-poly(ethylene glycol)-b-poly(ε-caprolactone) is a functionalized, amphiphilic, diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PCL block. These biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics). Additionally, well-defined nanoparticles with tunable size and properties can be prepared by altering the molecular weight ratios between hydrophilic and hydrophobic blocks, as well as by controlling formulation parameters. The carboxylic acid functional group on the PEG chain enables rapid and facile surface functionalization, allowing for these materials to be used in applications such as targeted drug delivery.

基本信息

线性分子式

C₃H₅O₃[C₂H₄O]_n[C₆H₁₀O₂]_mH

产品性质

质量水平	100
形式	powder or chunks
分子量	PCL average M_n 10,000 (by NMR) PCL average M_n 10,000 PEG average M_n 5,000 (by NMR) PEG average M_n 5,000
颜色	white to beige
储存温度	−20℃
SMILES string	[H]OCCCCCC(OCCOCCC(O)=O)=O

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable